Grey's Anatomy - Season 4 (2007) (season)
Creators:
Shonda RhimesDirected by:
Jeff MelmanCinematography:
Herbert DavisComposer:
Danny LuxCast:
Ellen Pompeo, Justin Chambers, Chandra Wilson, James Pickens Jr., Sandra Oh, Katherine Heigl, T.R. Knight, Sara Ramirez, Eric Dane, Chyler Leigh, Brooke Smith, Patrick Dempsey, Jeff Perry (more)VOD (2)
Plots(1)
George and Izzie's romantic chemistry is put to the test. Mark develops a crush on a fellow surgeon. Callie's role as chief resident is in jeopardy. (iTunes)
Cast
![Ellen Pompeo](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/163/134/163134840_74c4d0.jpg)
Ellen Pompeo
USA
Best series:
Friends (1994) (series)
The Job (2001) (series)
Grey's Anatomy (2005) (series) - actor, a.f.
![Justin Chambers](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/162/937/162937665_2c81ad.png)
Justin Chambers
USA
Best series:
The Offer (2022) (series)
Grey's Anatomy (2005) (series) - actor, a.f.
Private Practice (2007) (series)
![Chandra Wilson](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/163/058/163058340_d5492f.png)
Chandra Wilson
USA
Best series:
The Sopranos (1999) (series)
Grey's Anatomy (2005) (series)
Third Watch (1999) (series)
![James Pickens Jr.](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/166/038/166038392_a13cbb.jpg)
James Pickens Jr.
USA
Best series:
Six Feet Under (2001) (series)
The X-Files (1993) (series)
Grey's Anatomy (2005) (series)
![Sandra Oh](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/163/751/163751064_0261c6.jpg)
Sandra Oh
Canada
Best series:
Invincible (2021) (series)
Six Feet Under (2001) (series)
She-Ra and the Princesses of Power (2018) (series)
![Katherine Heigl](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/162/933/162933971_72fd46.jpg)
Katherine Heigl
USA
Best series:
Suits (2011) (series)
Firefly Lane (2021) (series)
Grey's Anatomy (2005) (series) - actor, a.f.
![T.R. Knight](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/165/003/165003883_e18b10.jpg)
T.R. Knight
USA
Best series:
Genius (2017) (series) - actor, a.f.
11.22.63 (2016) (series)
The Comey Rule (2020) (series)
![Sara Ramirez](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/163/063/163063436_fc252b.png)
Sara Ramirez
Mexico
Best series:
Spin City (1996) (series)
Grey's Anatomy (2005) (series) - actor, a.f.
Third Watch (1999) (series)
![Eric Dane](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/163/017/163017976_3cca1d.jpg)
Eric Dane
USA
Best series:
The Wonder Years (1988) (series)
Euphoria (2019) (series)
Grey's Anatomy (2005) (series) - actor, a.f.
![Chyler Leigh](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/162/466/162466038_f9cb1a.png)
Chyler Leigh
USA
Best series:
Grey's Anatomy (2005) (series) - actor, a.f.
Private Practice (2007) (series)
The Flash (2014) (series)
![Brooke Smith](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/165/118/165118199_e5ba7e.jpg)
Brooke Smith
USA
Best series:
Six Feet Under (2001) (series)
Bosch (2014) (series)
Ray Donovan (2013) (series)
![Patrick Dempsey](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/164/912/164912996_ed43e6.jpg)
Patrick Dempsey
USA
Best series:
The Truth About the Harry Quebert Affair (2018) (series)
Grey's Anatomy (2005) (series) - actor, a.f.
Private Practice (2007) (series)
![Jeff Perry](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/166/053/166053454_d62ac5.jpg)
Jeff Perry
USA
Best series:
My So-Called Life (1994) (series)
Prison Break (2005) (series)
Fringe (2008) (series)
![Rockmond Dunbar](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/000/276/276045_c1f8fc.jpg)
Rockmond Dunbar
USA
Best series:
Prison Break (2005) (series)
Sons of Anarchy (2008) (series)
9-1-1 (2018) (series)
![Stephanie March](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/159/463/159463577_8b7ce3.jpg)
Stephanie March
USA
Best series:
Grey's Anatomy (2005) (series)
Solar Opposites (2020) (series)
30 Rock (2006) (series)
![Vicki Lewis](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/162/882/162882903_ea0e81.jpg)
Vicki Lewis
USA
Best series:
The Norm Show (1999) (series)
Grey's Anatomy (2005) (series)
Curb Your Enthusiasm (2000) (series)
David Burke
USA
Best series:
House M.D. (2004) (series)
How to Get Away with Murder (2014) (series)
Frasier (1993) (series)
![Kurt Fuller](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/000/273/273954_8279eb.jpg)
Kurt Fuller
USA
Best series:
Avatar: The Last Airbender (2005) (series)
House M.D. (2004) (series)
Carnivàle (2003) (series)
![Enuka Okuma](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/163/220/163220837_d39226.jpg)
Enuka Okuma
Canada
Best series:
Steven Universe (2013) (series)
Traders (1996) (series)
How to Get Away with Murder (2014) (series)
![Braeden Lemasters](http://image.pmgstatic.com/cache/resized/w88h116crop/files/images/creator/photos/166/193/166193590_164fb9.jpg)
Braeden Lemasters
USA
Best series:
House M.D. (2004) (series)
Six Feet Under (2001) (series)
11.22.63 (2016) (series)